Larry Fitzgerald has been on many bad teams in his 15 years with the Arizona Cardinals.

This Nick Mullens Jersey , though, is the first time he's endured an 0-4 start to the season.Still, despite a sore hamstring, Fitzgerald soldiers on."It's not difficult at all," he said after Thursday's practice. "I'm a creature of habit. This is what I've been doing since I was 6 years old at this time of year. I don't look at it like it's any different. I prepare the same way every single week. There are some good weeks and some bad weeks. That's the way it goes."While coach Bruce Arians and quarterback Carson Palmer retired after last season, Fitzgerald chose to come back.But he's been part of an offense that has been the worst in the NFL. With career statistics that rank among the best in the game, Fitzgerald has 15 catches for 141 yards through four games. That puts him on pace for 60 catches this season, which would be his fewest since his rookie season.By comparison, Fitzgerald matched his franchise record with 109 catches, second-most in the NFL, for 1,156 yards and six TDs a year ago. He has 325 receptions over the past three years, including an NFL-best 107 in 2016 and 109 in 2015.But this is a new offense under coordinator Mike McCoy, who says he wants to get the ball to Fitzgerald more as the Cardinals prepare for Sunday's game at San Francisco.Fitzgerald is the unquestioned leader of an otherwise very young group of receivers. He doesn't plan on changing anything."You've got to stay the course, lead by example," he said. "This doesn't feel nearly as bad as starting 4-0 and dropping eight in a row (which happened in 2012). And so there's always been worse scenarios. Obviously, we're frustrated. We know we have to play better."Fitzgerald has 2 Nick Mullens 49ers Jersey ,169 career yards receiving against the 49ers, the most he has against any opponent. In NFL history, only Jerry Rice has more yards against a single opponent."We've got a great opportunity this weekend," Fitzgerald said. "This is a team that we're familiar with in terms of personnel and what they do schematically. So there's no better opportunity than the present one."Fitzgerald said that, despite the offense's problems, McCoy "has done a great job.""It doesn't matter what the call is honestly," Fitzgerald. "It's the players who are executing. We have to do a better job."Fitzgerald and the rest of the Cardinals' offense are encouraged by the emergence of rookie Josh Rosen at quarterback. Rosen had a strong debut in his first start in Sunday's 20-17 loss to Seattle, even though he had five passes dropped, two uncharacteristically by Fitzgerald.Rosen's ability to make plays downfield should open up the mid-range passing that is Fitzgerald's forte at this point in his career."I think it opens up for everybody," Fitzgerald said, "the running game, the intermediate passing game and obviously the chunk shots. We had some good chunk plays last week. Hopefully, we can continue to build on that."Asked if he wants to be a bigger part of the offense, with more targets, Fitzgerald just shrugs the question off."I'm never one to complain or ask for anything. If it comes my way, it comes my way," he said. "I'm not going to lose any sleep."Fitzgerald has been effusive in his praise of Rosen."Even before he was starting he took a leadership role. He's taken leadership a long time ago Quarterback Nick Mullens Jersey ," Fitzgerald said. "This is his team. He'll be the guy here for the next 10-plus years, God willing. I love the way he's kind of taken the reins, is vocal, lets people know exactly what he wants. He wants the best out of everybody."Rosen has said he wants to talk Fitzgerald into playing beyond this season.When told about that, the 35-year-old receiver just smiled."Hopefully, I'll be one of his biggest cheerleaders," Fitzgerald said. The injury news could have been worse regarding Matt Breida, but it appears the San Francisco 49ers will be without their top running back for at least one game.Breida underwent an MRI on Monday that showed a "serious sprain" to his left ankle, according to coach Kyle Shanahan. That likely will sideline Breida for next Monday night's game at Green Bay."It was positive news that it wasn't a high ankle sprain, (but) he'll probably end up being doubtful this week," Shanahan said.As the 49ers look to rebound from Sunday's deflating 28-18 home loss to the Arizona Cardinals, they'll probably have to do so without the player who's been their best offensive weapon, so far.Breida ranks fifth in the NFL with 369 rushing yards, and his 7.5 yards per carry average leads the league among those with at least 25 rushing attempts. He enjoyed a terrific first quarter Sunday before leaving with his ankle injury.Breida has been a bright spot for the struggling 49ers (1-4), who lost projected starting running back Jerick McKinnon to a torn ACL in the preseason and then watched No. 1 quarterback Jimmy Garoppolo suffer the same season-ending injury in Week 3 against Kansas City.Without Breida, the 49ers would lean heavily on veteran Alfred Morris, who has shared ball-carrying duties with Breida and is more of a between-the-tackles runner.Raheem Mostert is third on the depth chart Nick Mullens Jersey , but he's more of a special-teams contributor and he fumbled his first carry Sunday after Breida left the game.It wasn't a surprise that the 49ers brought in several running backs for workouts Monday afternoon. One of them was Jeremy McNichols, who was among San Francisco's training camp cuts this summer.Shanahan said the team would decide later in the week whether to sign a running back. Another option is promoting Jeff Wilson from the practice squad if Breida can't play Monday at Green Bay.The 49ers will take a two-day break before returning to the practice field Thursday to begin preparing for their prime-time game against the Packers.Figure a point of emphasis will be protecting the ball better, after San Francisco committed five turnovers in Sunday's loss to the previously winless Cardinals. It was the most turnovers for the 49ers since they had five against Seattle on Sept. 15, 2013.But another challenge for Shanahan is keeping his players mentally focused. Many viewed the 49ers as a potential playoff team before the season. Instead, they've lost four of their first five games and suffered a psychological blow when Garoppolo went down."It's different in this day and age where you hear everything," Shanahan said. "It's hard to simplify your world. And with social media, when guys go home, even if guys don't listen to things, their wives do. Their girlfriends do. Their brothers do."When you go through that stuff and don't meet outside expectations, it starts to affect you. And I just try to constantly preach to our guys to be stronger than that, to try to not pay attention to that, because that's not going to help you solve any problems."NOTES: Receiver/punt returner Dante Pettis (left knee) already has been ruled out for a second consecutive game. Several others will be re-evaluated once the team returns to practice Thursday. They include receiver Marquise Goodwin (quad, hamstring), left tackle Joe Staley (knee), center Weston Richburg (knee), tight end George Kittle (knee) and cornerback Jimmie Ward (hamstring).